Tuesday, September 22, 2009

Avastin

Sorry to have been gone so long.

Last month, my CA125 jumped from 19 to 24. That spurred me to request a CT scan, and my doc was definitely on board with that. We waited a month, and I had the scan this past Friday, and a doctors appointment yesterday.

The scan showed both good news and bad news. The good news is - still no NEW cancer growth! Wow! That is pretty amazing, and I believe it must be the vaccine that is preventing any new cancer implants.

The bad news is - the stuff that is there (nodules throughout my abdomen) has grown. Mostly, they have only grown only about 1/2 cm each in the three months since my last scan. My CA125 is up to 26 now as well. Although upsetting, this news was not wholly unexpected (since my CA125 had been creeping up).

So, we discussed options. The doc mentioned several different strategies. We can wait a few more months before doing anything - we can try hormonal therapy (I have to ask her more about this in the future) - I can have another surgery, and then have heated chemotherapy applied directly in my abdomen - or we can try Avastin. She really thought that the Avastin was the best option for me with "the minimal amount of cancer" that I currently have.

Avastin is a biological therapy (not really a chemo) that targets a protein found in many cancer cell teypes, and halts cancer growth. I think that it keeps the body from providing blood supply to cancer. (I will be researching this more). Usually, it is given in conjunction with chemotherapy drugs, but the doctor said that they have been using it as a single agent drug (meaning that Avastin is all I will be getting). I am happy about that, since I really have no faith in chemotherapy (I've been through three types so far, and none have worked in the least).

So I started treatment yesterday - nothing like jumping in feet first! :) I feel fine, and it is not supposed to really have many side effects. Of course, the side effects that it may have are bad. They are rare - but bad. For example - the worst would be bowel perforation. I may have high blood pressure, and have to take medication for it as a result of this medication. Also, it can cause some kidney problems. I have the treatment every three weeks - we will go three rounds, and then another scan to see if it is effective.

The big hope is that the Avastin takes care of the one lymph node that is located outside of my abdominal cavity (just outside of it). Then I would have surgery again to remove everything - and the heated chemotherapy directly into the abdomen. The heated chemo can only be used if cancer is confined to the abdominal cavity (for obvious reasons).

I will update again soon, I promise. Especially now that I am in full treatment again...

12 comments:

Maggie said...

I hate cancer. Well, Nat, at least your doc is being aggressive. No mamby-pamby approach. Keep your wonderful spirit up, and I will be thinking about you.
Maggie

l'optimiste said...

although I'm happy to hear from you, and the news is good and bad [glossing over the bad bit quickly!], I quite like it when you don't blog, as I know you're ok.

Here's hoping the Avastin does the trick. Typical of you to go hell bent for leather ;o)
xxx

Anonymous said...

I'm very happy that it is contained and only growing slowly. I had avastin. I think it gave me bloody noses but that could have been from the other two chemo drugs I was on at the same time (carbo and taxol).

I'm so sorry you have to go through any of it.

Anonymous said...

Hi Natalie - Gosh! I'm sorry to hear the CA125 went up, and now you'll be on that drug Avastin. It sure sounds like you have a great doctor, and you sure don't let any grass grow under your feet before you jump right in. I hope those side affects don't occur, and I will be keeping you and your favorite husband in my thoughts & prayers. Take care, God bless. xoxoxo Gerry

Joshua Sophy said...

Here is more info on the risks associated with Avastin: http://www.newsinferno.com/archives/13112

Kia Taylor said...

Hey Nat, Sounds like a good plan...please keep us updated. I've heard good things about the avastin...I think you're results will be great!!

XOXO

Jamie said...

Hey Nat!!! I have checked periodically, and there usually was nothing. Now today I see that you are back in treatment. I'm sorry that you have to start going through this again, but, it does sound promising!!! I'm glad you switched to this new doctor. I wish we would have done that with my mom. Although I think it was just too far progressed when they found it in the first place. Good luck to you! I will be praying for you! Keep us posted and hang in there.

RonM said...

Hey ... I read that you started your treatment with Avastin ... I thought you might want to know that Avastin is not is cure, my wife was the longest living survivor, but that was 3.5 years ago and things have changed since then. ... it will keep the disease from progressing but only for a time. Take the time that you do have and use it for reasearch and find a new treatment.
Wishing you all the best,
Ron

Lakeland Jo said...

Just popped over from L'optimiste. Sending positive thoughts
X

Joellyn said...

I'm thinking of you, Nat. I have heard some pretty good things about Avastin from a woman in my community. She recommended it pretty highly. I hope the side effects are minimal. Please keep us posted!

koneill1976 said...

Hey nat, I haven't talked to you in a long time either. The one ovary they did not take out has a mass in it again. :( They are just watching it for now b/c my doctor doesn't want me to deal with the side effects of no ovary. I would rather them take it out. On you, as usual, you are a role model. I am thinking of you and do almost everyday wondering how you are doing. Glad you are researching everything. I do that too.

Stay strong
your are in my thoughts
kristine

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